Left atrial appendage orifice area and morphology is closely associated with flow velocity in patients with nonvalvular atrial fibrillation

Abstract Background Thromboembolic events are the most serious complication of atrial fibrillation (AF), and left appendage (LAA) is important site thrombosis in patients with AF. During period COVID-19, a non-invasive detection method particularly order to reduce exposure virus. This study used CT three-dimensional reconstruction methods explore relationship between LAA morphology, orifice area its mechanical function non-valvular (NVAF). Methods A total 81 consecutive NVAF (36 cases paroxysmal 45 persistent fibrillation) who were planned undergo catheter radiofrequency ablation enrolled. All examined by transthoracic echocardiography (TTE), TEE, computed tomography angiography (CTA) before surgery. The was obtained according images CTA. According it divided into chicken wing type non-chicken type. At same time, TEE performed determine flow velocity (LAAFV), LAAFV analyzed. Results Non-chicken group lower than that Chicken (36.2 ± 15.0 cm/s vs. 49.1 22.0 cm/s, p -value < 0.05). In subgroup analysis, AF (44.0 14.3 60.2 22.8 AF, similar results observed (29.7 12.4 40.8 17.7 (34.6 15.8 49.9 20.0 0.001). negatively correlated dimension (R = − 0.451, 0.001), (R= 0.438, 0.001) ventricular mass index (LVMI) 0.624, while positively LVEF 0.271, 0.014). Multiple linear regression analysis showed morphology (β 0.335, 0.185, 0.033), 0.167, 0.043) LVMI 0.465, independent factors LAAFV. Conclusions closely related NVAF. larger LVMI, predictors decreased LAA, these parameters might be helpful for better management LA thrombosis.